University of Nottingham
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endotracheal tube pressure sensor

iTraXS Novel endotracheal tube

for safer intubation in critical care


In critically ill patients, and under anaesthesia, endotracheal tubes play a vital role in maintaining an open airway, allowing artificial ventilation, and preventing aspiration of fluid into the lungs.

However, artificial ventilation, whilst necessary, often leads to other serious conditions such as post-intubation stenosis, affecting a patient’s ability to breathe and speak, and  ventilator-associated pneumonia, which prolongs recovery and can be fatal. These complications are influenced by tracheal cuff design and use, in particular the quality of the contact between the cuff and the trachea, the pressure applied, and the effect of this pressure on local tracheal blood flow.

Avoiding tracheal damage and ventilator-associated pneumonia

Developed with NIHR i4i funding (II-LA-0813-20008), our iTraXS (intra tracheal multiplexed sensing) tube has incorporated optical fibre sensors into the cuffs of the tube which can measure tracheal contact pressure and blood flow, humidity, temperature, oxygen saturation and biofilm thickness. We aim to be able to optimise the level of inflation of the seal of the endotracheal tube to minimize tracheal injury during intubation as well as reduce the incidence of pneumonia.

In collaboration with medical device company P3 Medical and anaesthetists from Nottingham University Hospitals NHS Trust, we have successfully completed proof of principle studies including our first in human series.
Endotracheal tube P3 package




Professor Steve Morgan

Professor of Biomedical Engineering, Faculty of Engineering

Dr Andy Norris

Consultant Anaesthetist & Honorary (Clinical) Associate Professor

Dr Ricardo Correia

Assistant Professor in Optical and Bioelectronic Engineering, Faculty of Engineering

Professor Jon Hardman

Professor & Consultant in Anaesthesia, Faculty of Medicine & Health Sciences


Key Papers

Optical fibre sensing at the interface between tissue and medical device

Optical fibre sensing during critical care